Precisely engineered for more gradual digestion.
SiPore® is a patented technology based on precisely engineered porous silica particles. It works locally in the gut, where its controlled pores entrap a portion of digestive enzymes involved in breaking down carbohydrates and fats. This slows digestion so energy from the meal enters the system more gradually. SiPore® does not enter the bloodstream. It has also been generally well tolerated in human research.
Watch the filmHow SiPore® works0:48One technology. Three simple steps.
- 1. EATCarbohydrates and fats enter the digestive system.
- 2. ENTRAP + SLOWSiPore®’s precisely engineered pores entrap a portion of digestive enzymes.
- 3. MORE GRADUALCarbohydrates and fats are broken down more gradually, helping energy from the meal enter the system more gradually.
The function is in the pores.
SiPore® is based on porous silica particles with a precisely controlled internal structure. The pores are engineered for their function during digestion. Their structure allows SiPore® to interact physically with digestive enzymes while the particles remain within the gastrointestinal tract.
Precisely engineered. The pore structure is not decorative. It is what gives the technology its function during digestion.
Entrapping a portion of the enzymes that break down the meal.
Digestive enzymes help break down the carbohydrates and fats in food into smaller components the body can use. During digestion, SiPore®’s engineered pores can entrap a portion of enzymes such as amylase and lipase. With fewer enzymes freely available during part of the digestive process, carbohydrates and fats are broken down more gradually.
Designed to work where digestion happens.
SiPore® works locally in the gastrointestinal tract, where digestion happens. It does not need to enter the bloodstream to work. Instead, its precisely engineered porous particles interact with digestive enzymes while carbohydrates and fats from the meal are being broken down.
Studied in people. Generally well tolerated.
SiPore® has been evaluated in human clinical research, including dedicated safety and tolerability research. Across the human evidence base, SiPore® has been generally well tolerated. SiPore® has been developed through more than 15 years of research, progressing from fundamental and preclinical work into human clinical evaluation.
Slowing digestion is not the same as stopping digestion.
SiPore® is not designed to stop digestion. It does not eliminate digestive enzymes or “block” carbohydrates and fats. Instead, it entraps a portion of digestive enzymes and slows the breakdown of carbohydrates and fats. The result is more gradual digestion and more gradual energy delivery.
Slower breakdown More gradual digestion Gut-local action Partial enzyme entrapment More gradual energy delivery
A carb blocker A fat blocker A systemic intervention Elimination of digestive enzymes Stopping absorption
No loading period is required for the mechanism to begin.
SiPore®’s local mechanical mode of action begins during digestion of the first meal it is used with. There is no loading period required before the mechanism can begin.
SiPore® begins performing its local function during digestion of the first meal it is used with.
Longer-term outcomes require repeated use and must be understood within the timeframe of the relevant research.
Works from the first meal. Its local mode of action begins with the first meal it is used with.
Five things to remember about SiPore®.
Built on more than 15 years of research.
SiPore® has progressed from fundamental and preclinical research through human clinical evaluation. Explore the evidence behind the technology, including clinical studies, mechanism research, safety and tolerability, and peer-reviewed publications.
Modern food delivers energy fast. SiPore® slows it down.
The meal companion for modern food.