Appetite Control, Weight Loss, and Muscle Preservation
1-month real-world-evidence study (n=80) lead by Chris D’Adamo, PhD, University of Maryland. 80 overweight American adults took Carb Fence, powered by SiPore®, 3× daily for 1 month, with their normal diet and activity.

Source: U.S. Real-World Evidence Study, 2025 (N=80)
62% of participants lost weight in just 4 weeks.
Average weight loss among responders: 4.2 lbs, preserving muscle mass. Results with normal diet and activity.
Significant reductions reported by participants.
Satiety was surveyed at the start and at the end of the month.
Excellent tolerability.
One month of everyday use, measured daily.
The study followed adults in their normal routines, without changes to diet or activity.
80 overweight American adults Carb Fence, 3× daily for 1 month Body composition scale: daily measure Satiety survey at start and end
Real-world evidence is observational: it shows what is observed in everyday use, not the results of a controlled clinical trial.

Led by Chris D’Adamo, PhD.
University of Maryland. 100+ peer-reviewed publications. Expert in nutrition and lifestyle medicine.

Chris D’Adamo
PhD, University of Maryland
One part of a broader evidence program.
Real-world evidence adds what is observed in everyday use to SiPore®’s controlled clinical studies, consumer research and preclinical science.