--- title: "Technology" description: "SiPore® is a patented technology based on precisely engineered porous silica particles that work locally in the gut, slowing digestion so energy from the meal enters the system more gradually." url: "https://sipore.com/technology" canonical: "https://sipore.com/technology" markdown_url: "https://sipore.com/technology.md" site: "SiPore" publisher: "SiPore Technologies (Sigrid Therapeutics AB)" language: "en" updated: "2026-10-05" --- # Technology > SiPore® is a patented technology based on precisely engineered porous silica particles that work locally in the gut, slowing digestion so energy from the meal enters the system more gradually. *SIPORE® TECHNOLOGY* ## Precision engineered for more gradual digestion. SiPore® is a patented technology based on precisely engineered porous silica particles. It works locally in the gut, where its controlled pores entrap a portion of digestive enzymes involved in breaking down carbohydrates and fats. This slows digestion so energy from the meal enters the system more gradually. SiPore® does not enter the bloodstream and has been generally well tolerated in human research. [Watch how SiPore® works →](#how-it-works) *HOW SIPORE® WORKS* ### One technology. Three simple steps. - 1. EAT — Carbohydrates and fats enter the digestive system. - 2. ENTRAP + SLOW — SiPore®’s precisely engineered pores entrap a portion of digestive enzymes. - 3. MORE GRADUAL — Carbohydrates and fats are broken down more gradually, helping energy from the meal enter the system more gradually. *THE ENGINEERED PARTICLE* ### The function is in the pores. SiPore® is based on porous silica particles with a precisely controlled internal structure. The pores are engineered for their function during digestion. Their structure allows SiPore® to interact physically with digestive enzymes while the particles remain within the gastrointestinal tract. > **Precisely engineered.** > The pore structure is not decorative. It is what gives the technology its function during digestion. *DIGESTIVE ENZYME ENTRAPMENT* ### Entrapping a portion of the enzymes that break down the meal. Digestive enzymes help break down the carbohydrates and fats in food into smaller components the body can use. During digestion, SiPore®’s engineered pores can entrap a portion of enzymes such as amylase and lipase. With fewer enzymes freely available during part of the digestive process, carbohydrates and fats are broken down more gradually. - AMYLASE — Helps break down carbohydrates. - LIPASE — Helps break down fats. - A PORTION — NOT ALL — SiPore® does not eliminate digestive enzymes. *GUT-LOCAL BY DESIGN* ### Designed to work where digestion happens. SiPore® performs its function locally in the gastrointestinal tract. It does not need to enter the bloodstream to work. Instead, its precisely engineered porous particles interact with digestive enzymes while carbohydrates and fats from the meal are being broken down. - WORKS LOCALLY IN THE GUT — Its function takes place in the gastrointestinal tract. - DOES NOT ENTER THE BLOODSTREAM — SiPore® remains local rather than acting systemically. - ACTS DURING DIGESTION — Its role is directly connected to the processing of the meal. *SAFETY & TOLERABILITY* ### Studied in people. Generally well tolerated. SiPore® has been evaluated in human clinical research, including dedicated safety and tolerability research. Across the human evidence base, SiPore® has been generally well tolerated. The technology has been developed and clinically evaluated over more than 15 years of research. [Explore Safety & Tolerability →](https://sipore.com/science/safety-tolerability) *MORE GRADUAL, NOT BLOCKED* ### Slowing digestion is not the same as stopping digestion. SiPore® is not designed to stop digestion. It does not eliminate digestive enzymes or “block” carbohydrates and fats. Instead, it entraps a portion of digestive enzymes and slows the breakdown of carbohydrates and fats. The result is more gradual digestion and more gradual energy delivery. *NO LOADING PERIOD* ### No loading period is required for the mechanism to begin. SiPore®’s local mechanical mode of action begins during digestion of the first meal it is used with. There is no loading period required before the mechanism can begin. - Meal 1 - Digestion begins - SiPore® mechanism begins > **Works from the first meal.** > Mechanism onset, not a promise of immediate long-term outcomes. *TECHNOLOGY IN ONE VIEW* ### Five things to remember about SiPore®. - PRECISELY ENGINEERED — Controlled porous silica structure designed for its function during digestion. - ENZYME ENTRAPMENT — Entraps a portion of enzymes involved in carbohydrate and fat digestion. - GUT-LOCAL — Works in the gastrointestinal tract and does not enter the bloodstream. - GENERALLY WELL TOLERATED — Evaluated across human clinical research. - FIRST-MEAL ACTION — Its local mechanical mode of action begins during digestion of the first meal it is used with. *FROM TECHNOLOGY TO EVIDENCE* ### Built on more than 15 years of research. SiPore® has progressed from fundamental and preclinical research through human clinical evaluation. Explore the evidence behind the technology, including clinical studies, mechanism research, safety and tolerability, and peer-reviewed publications. ### Modern food delivers energy fast. SiPore® slows it down. The meal companion for modern food. [Explore the science →](https://sipore.com/science) [Why SiPore® →](https://sipore.com/why-sipore) ## How to cite SiPore Technologies (Sigrid Therapeutics AB). “Technology”. SiPore, 2026-10-05. https://sipore.com/technology (accessed ). Use the trademarks as written: SiPore®, Carb Fence™. For the SHINE trial, cite the peer-reviewed publication in *eClinicalMedicine* (The Lancet Discovery Science, 2026) rather than this page. ## Company & contact - **Company:** SiPore Technologies — legal entity Sigrid Therapeutics AB (Swedish org.nr [556958-3023](https://www.allabolag.se/foretag/sigrid-therapeutics-ab/sundbyberg/forskning/2K3ZHRJI5YE3M)) - **Stockholm headquarters:** Vasagatan 14A, 172 61 Sundbyberg, Sweden ([map](https://www.google.com/maps/search/?api=1&query=Vasagatan%2014A%2C%20172%2061%20Sundbyberg%2C%20Sweden)) - **General enquiries:** [contact@sipore.com](mailto:contact@sipore.com) - **Partnerships & licensing:** [partnerships@sipore.com](mailto:partnerships@sipore.com) - **Origin:** Founded in Stockholm, Sweden - **Taglines:** “The meal companion for modern food.” · “Same meal. Less impact.” · “Scandinavian science. Global impact.” · “Precision science for the modern meal.” - **About:** SiPore® is a patented meal-companion technology designed to reduce the impact of modern meals at the level of digestion. **Our sites** — all sites owned and operated by Sigrid Therapeutics AB: - [SiPore.com](https://www.sipore.com/): Technology, science & partnerships - [SiPorePro.com](https://www.siporepro.com/): Practitioner products & professional resources - [SigridLife.com](https://sigridlife.com/): SIGRID consumer products - [SigridStabiliser.se](https://sigridstabiliser.se/): SIGRID Sweden --- [View on site](https://sipore.com/technology) · [Site index for agents (llms.txt)](https://sipore.com/llms.txt)